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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Interaction of hepatitis B virus proteins with mechanisms of innate immunity
 Vávrová, Petra ; Hirsch, Ivan (advisor) ; Horníková, Lenka (referee)
Specific aim of this bibliographic research is to elucidate interaction of hepatitis B virus proteins with mechanisms of the innate immunity. The work will specially analyze the role of viral proteins before and after their transport from the infected cell. Because of the central role of cccDNA for virus persistence in human organism, the work will study the effects of restriction factors on its possible destruction and eradication. The research will be focused on the effect of viral proteins during acute, chronic and occult infection.
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Effect of restriction factors on replication of hepatitis B virus
 Kunteová, Kateřina ; Hirsch, Ivan (advisor) ; Sýkora, Michal (referee)
Specific aim of this bibliographic research is to elucidate the effects of cellular restriction factors on HBV replication. The work will specially analyze the role of the innate and natural immunity and to compare the effect of analogical or identical restriction factors on HBV and HIV-1 replication. Because of the central role of cccDNA for virus persistence in human organism, the work will study the effects of restriction factors on its possible destruction and eradication and a possible HBV cure. The research will also be focused on the effect of restriction factors during acute, chronic and occult infection. Powered by TCPDF (www.tcpdf.org)
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